Ciflo Special Precautions

250 mg: Ciprofloxacin should only be administered to patients with a history of seizures if appropriate and effective seizure prevention or treatment measures are available. The absorption of Ciflo is reduced when co-administered with antacids containing aluminum or magnesium hydroxide; therefore, these medications should not be taken simultaneously. Ciflo should be taken 1 to 2 hours before or after antacids. Additionally, coadministration of Ciprofloxacin (1,500 mg or more per day) with theophylline may lead to elevated blood concentrations of theophylline, exceeding the desired therapeutic levels.
500 mg: Use with caution in patients with a history of epilepsy or other neurological disorders and patients with kidney disease.
This drug may cause nausea, vomiting, dizziness, headache, nervous system stimulation (causing insomnia, confusion, hallucinations and seizures), kidney inflammation, tendonitis or tendon rupture, skin sensitivity to sunlight and severe allergic reactions.
After using this medicine, if the patient experiences joint pain or tendonitis, stop taking the medicine and consult a doctor immediately.
This drug should not be taken with didanosine, sucralfate, antacids containing aluminum, magnesium, vitamins containing iron, zinc, and calcium because these drugs reduce the absorption of ciprofloxacin. If necessary, take at least 2 hours after taking ciprofloxacin.
This drug should not be used together with theophylline, caffeine, aminophylline, digoxin, cyclosporin, and the anticoagulant warfarin because ciprofloxacin inhibits the breakdown of these drugs, causing dangerously high levels of the drug.
Use in Pregnancy & Lactation: See USE IN PREGNANCY & LACTATION section for further information.
Use in Children: 500 mg: This medicine should not be used in people under the age of 18 years.