Ciflo Dosage/Direction for Use

250 mg: Ciflo should be taken twice a day, in the morning and evening.
Cystitis: Take ½-1 tablet twice a day.
Respiratory tract, urinary tract, kidney and gastrointestinal infections (including typhoid fever): Take ½ tablet twice a day.
Other infections: Take 2 tablets twice a day.
Severe infections: The dosage can be increased to 3 tablets twice a day.
Acute gonorrhea in both men and women, including uncomplicated acute cystitis: Take only 1 tablet once.
Take medicine with water on an empty stomach. The drug will be absorbed more quickly.
The duration of treatment depends on the severity of the disease. It is usually given for 5-10 days. After the fever subsides or the symptoms of the disease disappear, the drug should be continued for at least 3 days.
In uncomplicated urinary tract infections, a treatment period of 3 days should be sufficient.
In patients with abnormal blood function, the creatinine clearance is less than 20 ml/min. Use the normal dosage. It may be given only once daily, or if twice daily is desired, reduce the dosage by half.
500 mg: Recommended dose: Adults: Take 250-750 mg twice daily, every 12 hours. The maximum dose per day is not more than 1.5 grams. The duration of treatment depends on the site of infection and the severity of the disease, as follows: Urinary tract infections: Take 250-500 mg twice daily, every 12 hours, for at least 7-14 days. Longer doses may be needed if the infection is severe or has complications.
Gonorrhea caused by Neisseria gonorrhoeae: Take 250-500 mg once.
Infectious diseases of the digestive tract: Take 500 milligrams twice daily, every 12 hours, for 5-7 days.
Typhoid fever: Take 500 milligrams twice daily, every 12 hours, for 10 consecutive days.
Lower respiratory tract infections, skin and soft tissue infections, bones and joints: Take 500-750 mg twice daily, every 12 hours for 7-14 days. Bone infections may require longer-term medication for 4-6 weeks.
Patients with impaired kidney function: The dosage should be reduced according to creatinine clearance (Cr_Cl), with the infusion interval adjusted from every 12 hours (Cr_Cl 30-50 mL/min) to every 18-24 hours when Cr_Cl is between 5-29 mL/min. For those undergoing hemodialysis or peritoneal dialysis, the infusion should be given every 24 hours after dialysis.
Children: This drug is not recommended for use in children as it has been shown to cause osteoarthritis in laboratory animals. However, if necessary, it might be given in doses of 10-20 mg/kg every 12 hours and as directed by a physician.
Notations: Should be taken with at least 1 glass of water (240 ml).
Take the medication continuously until the required treatment period is complete.
Do not drink milk or take antacids, sucralfate, iron or zinc-containing drugs, such as multivitamin products, within 2 hours before or after taking this medication, as this will reduce the absorption of the drug.
Do not take drugs that cause alkaline urine, such as citrates, bicarbonate of soda, or drugs that inhibit the action of the carbonic anhydrase enzyme, as this may cause kidney stones.
If the patient forgets to take the medicine, take it as soon as the patient remembers. However, do not take a double dose.
Sun exposure should be avoided during the period of treatment with this medicine.