Adenozin Dosage/Direction for Use

Recommended Dose: Dosage and Method of Administration: Adenosine injection is intended for hospital use only with monitoring and cardio respiratory resuscitation equipment available for immediate use.
Method of Administration: It should be administered by intravenous (IV) bolus injection according to the ascending dosage schedule as follows. To be certain the solution reaches the systemic circulation administer either directly into a vein or into an IV line. If given into an IV line it should be injected as proximally as possible, and followed by a rapid saline flush.
Adenosine Injection should only be used when facilities exist for cardiac monitoring. Patients who develop high-level AV block at a particular dose should not be given further dosage increments.
Posology: Adults: Initial Dose: 3 mg given as a rapid intravenous bolus (over 2 seconds).
Second Dose: If the first dose does not result in elimination of the supraventricular tachycardia within 1 to 2 minutes, 6 mg should be given also as an intravenous bolus.
Third Dose: If the second dose does not result in elimination of the supraventricular tachycardia within 1 to 2 minutes 12mg should be given also as an intravenous bolus. Additional or higher doses are not recommended.
Pediatric Population: Less than 50 kg: Initial dosage: 0.05 - 0.1mg/kg as an intravenous bolus given centrally or peripherally.
Second Dose: If conversion of PSVT does not occur within 1 - 2 minutes, additional bolus injections can be administered at incrementally higher doses, increasing the amount given by 0.05 - 0.1 mg/kg. Continue this process until sinus rhythm is established or a maximum single dose of 0.3 mg/kg (up to 12 mg) is used.
Maximum dose: 0.3mg/kg single dose (up to 12mg).
Diagnostic Dose: The previously mentioned ascending dosage schedule should be employed until sufficient diagnostic information has been obtained.
Method of Administration: Intravenous injection only.