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Pregnancy: As a general rule, the administration of diuretics should be avoided in pregnant women and should never be used to treat physiological edema of pregnancy. Diuretics can cause fetoplacenlal ischemia, with a risk of impaired fetal growth.
Lactation: Thiazide Diuretics have been associated, during breastfeeding, with decrease or even suppression of milk lactation. There is lack of studies on the possible excretion of indapamide or its metabolites in human milk and hypersensitivity to sulfonamide-derived medicines and hypokalemia might occur, a risk to the infant cannot be excluded.
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