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It is permissible to use supportive measures in the event of an overdose, such as removing unabsorbed material from the gastrointestinal system, doing clinical monitoring, which may include getting an ECG, and initiating supportive medication if the patient's clinical situation dictates.
Diazeptin can be moderately adjusted. In clinical trials, during a 3- to 4-hour hemodialysis session, about 13.5% of the dosage was eliminated. If clinically suitable, prolonged hemodialysis might be taken into consideration. The dialyzability of sitagliptin by peritoneal dialysis is unknown.
Metformin overdoses have happened, involving over 50 grammes being consumed.
About 10% of instances included reports of instances include reports of hypoglycemia; however, no clear link between the medication and the condition has been found. It has been found that in about 32% of metformin overdose instances, lactic acidosis occurs.
Metformin can be dialyzed, and in optimal hemodynamic circumstances, its clearance can reach up to 170 mL/min.
Hemodialysis may therefore be helpful in clearing patients of accumulated medication if metformin overdosage is suspected.
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