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Adults with type 2 diabetes mellitus who are not responding well to their maximal tolerated dose of metformin alone or who are already receiving treatment with a combination of sitagliptin and metformin should consider using sitagliptin and metformin hydrochloride film-coated tablets as a supplement to diet and exercise to improve glycaemic control.
In individuals who are not satisfactorily managed on their maximal tolerated dose of both metformin and a sulphonylurea, sitagliptin and metformin hydrochloride film-coated tablets are suggested in conjunction with a sulphonylurea (i.e., triple combination treatment) as an addition to diet and exercise.
In individuals who are not getting enough exercise or food, sitagliptin and metformin hydrochloride film-coated tablets are recommended as a triple combination therapy along with a PPARγ agonist (thiazolidinedione).
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