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Take Metformin Hydrochloride + Sitagliptin film-coated tablets orally twice daily with meals.
Based on the patient's current regimen, effectiveness, and tolerability, individually determine the dosage of Metformin Hydrochloride + Sitagliptin film-coated tablets.
The maximum recommended daily dosage for metformin HCl and sitagliptin is 2000 mg and 100 mg, respectively.
In individuals who are not on metformin therapy, a starting dose of 500 mg metformin HCl and 50 mg sitagliptin should be administered twice daily. Gradual dose escalation is advised to minimise metformin's gastrointestinal adverse effects.
For patients receiving metformin treatment already, the initial dose should consist of 50 mg of sitagliptin administered twice daily, for a total of 100 mg of metformin taken daily. In patients receiving twice a day 850 mg of metformin HCl.
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