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Adults: The usual adult daily dose (in terms of Ceftriaxone) is 1-2 grams given once a day (or in equally divided doses twice a day) depending on the type and severity of the infection. The total daily dose should not exceed 4 grams.
Dosage regimen for (Ceftriaxone-Sulbactam) should be adjusted in patients with marked decrease in renal function (creatinine clearance of <30 mL/min) and to compensate for reduced clearance less than 15 mL/min patient should receive a maximum of 500 mg of sulbactam every 12 hours (maximum dose 1 gram of sulbactam).
Pediatric patients: For treatment of skin and soft tissue infections, the recommended total daily dose (in terms of Ceftriaxone) is 50-75 mg/kg given once a day or (in equally divided doses twice a day). The total daily dose should not exceed 1 gram.
For the treatment of acute bacterial otitis media: A single intramuscular dose of 50 mg/kg (not to exceed 1 grams) is recommended.
In the treatment of Meningitis: The initial therapeutic dose in terms of Ceftriaxone should be 100 mg/kg (not to exceed 4 grams). Daily dose may be administered once a day or in equally divided dose 12 hourly. The usual duration of therapy is 7-14 days.
For the treatment of serious infections other than meningitis: recommended total daily dose in terms of Ceftriaxone is 50-75 mg/kg given in divided doses every 12 hours.
The total daily dose (in terms of Ceftriaxone) should not exceed more than 2 grams.
Or as prescribed by a physician.
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