Swich Dosage/Direction for Use

Tablet: Route of administration: Oral.
The tablets should be taken with food for optimum absorption.
Adults and adolescents with normal renal function: Upper respiratory tract infections: Acute bacterial sinusitis: 200 mg twice daily.
Lower respiratory tract infections: Acute exacerbation of chronic bronchitis: 200 mg twice daily.
Bacterial Pneumonia: 200 mg twice daily.
Elderly: It is not necessary to modify the dose in elderly patients with normal renal function.
Children: Pediatric formulation of cefpodoxime is available for infants and children.
Hepatic Impairment: The dosage does not require modification in cases of hepatic impairment.
Renal Impairment: The dosage of cefpodoxime does not require modification if creatinine clearance exceeds 40 mL/min.
Below this value, pharmacokinetic studies indicate an increase in plasma elimination half-life and the maximum plasma concentrations, and hence the dosage should be adjusted appropriately. (See Table 3.)

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Suspension: Infants and Pediatric Patients (age 2 months through 12 years): See Table 4.

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Adults: Adults with normal renal functions: Upper respiratory tract infections: For upper respiratory tract caused by organisms sensitive to Cefpodoxime, including sinusitis. In tonsillitis and pharyngitis, Cefpodoxime should be reserved for recurrent or chronic infections, or for infections where the causative organism is known or suspected to be resistant to commonly used antibiotics. Sinusitis: 200 mg twice daily. Other upper respiratory tract infections: 100 mg twice daily. Lower respiratory tract infections: For lower respiratory tract infections caused by organisms sensitive to Cefpodoxime, including acute bronchitis, relapses or exacerbations of chronic bronchitis and bacterial pneumonia: 100-200 mg twice daily, dependent on the severity of the infection.
Urinary tract infections: Uncomplicated lower urinary tract infections: 100 mg should be taken twice daily.
Uncomplicated lower urinary tract infections: 200 mg should be taken twice daily.
Uncomplicated gonococcal urethritis: 200 mg should be taken as a single dose.
Skin and soft tissue infections: 200 mg should be taken twice daily.
Cefpodoxime should be taken during meals for optimum absorption.
Elderly: It is not necessary to modify the dose in elderly patients with normal renal function.
Hepatic Impairment: The dosage does not require modification in cases of hepatic impairment.
Renal Impairment: The dosage of Cefpodoxime does not require modification if creatinine clearance exceeds 40 mL/min.
Below this value, pharmacokinetic studies indicate an increase in plasma elimination half-life and the maximum plasma concentrations, and hence the dosage should be adjusted appropriately. (See Table 5.)

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NOTE: The unit dose is either 100 mg or 200 mg, depending on the type of infection.
Directions for reconstitution: Shake bottle to loosen the powder. Slowly add boiled and cooled water up to the arrow mark on the label and shake well. Add more water, if necessary to adjust the volume up to the arrow mark, to make 60 mL.