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When should the patient not take this medicine: If the patient is allergic to flurbiprofen or to any of the excipients listed in the product.
If the patient has previously shown hypersensitivity reactions (e.g., asthma, rhinitis, angioedema, bronchospasm or urticaria) in response to ibuprofen, acetylsalicylic acid (Aspirin) or other non-steroidal anti-inflammatory drugs (NSAIDs).
If the patient has active or history of recurrent peptic ulcer/haemorrhage (2 or more distinct episodes of proven ulceration or bleeding).
If the patient has a history of gastrointestinal bleeding or perforation, severe colitis, haemorrhagic or haematopoietic disorders related to previous NSAID therapy.
If the patient has severe heart failure, severe hepatic failure, or severe renal failure. (See Precautions.)
If the patient is in the last trimester of pregnancy.
If the patient is children under 12 years of age.
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