
Vaccine Vial Monitors (VVMs) are part of the label on Rotavirus Vaccine, Live Attenuated (Oral) supplied through Serum Institute of India Pvt. Ltd. The colour dot which appears on the label of the ampoule is a VVM. This is a time-temperature sensitive dot that provides an indication of the cumulative heat to which the ampoule has been exposed. It warns the end user when exposure to heat is likely to have degraded the vaccine beyond an acceptable level.
The interpretation of the VVM is simple. Focus on the inner square. Its colour will change progressively. As long as the colour of this square is lighter than the colour of the outer circle, then the vaccine can be used.
As soon as the colour of the inner square is the same colour as the outer circle or of a darker colour than the outer circle, then the ampoule should be discarded.
INSTRUCTIONS FOR USE To administer the vaccine orally: Clear the fluid from the dispensing tip by tapping the ampoule and holding it vertically.
Open the dosing ampoule by easy twist motion.
Administer the complete dose (2 ml) by gently squeezing the ampoule into infant's mouth toward the inner cheek until dosing ampoule is empty.