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Click on icon to see table/diagram/imageDosage for elderly and patients with renal failure: Dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.
Some renally-impaired or elderly patients being treated for hypertension may require a lower starting dose of 25 mg a day. If this dose is used, assessment of efficacy must be made carefully. This should include blood pressure measurement just prior to the next dose ("trough" blood pressure) to ensure that the treatment effect is present for a full 24 hours. (See Table 2.)
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