Tablet: Studies have shown that the use of corticosteroids in pregnancy had no adverse effects on the fetus in terms of psychological development or growth. It was reported that prolonged or repeated high doses increased the risk of intra-uterine growth retardation but this did not seem to be a problem following short term therapy. Use of prednisone in pregnancy and lactation necessitates the consideration of potential benefits of the drug weighed against the possible risks to the mother and the fetus.