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Tablet: Prednisone overdose may include symptoms such as fever, muscle or joint pain, nausea, dizziness, fainting, difficulty of breathing. Prolonged overuse can manifest as moon face, obesity, unusual hair growth, acne, loss of sexual function and muscle wasting. Large doses of prednisone may produce Cushingoid symptoms typical of adrenal cortex hyperactivity.
Adverse events should be treated symptomatically, with the prednisone dosage reduced or slowly withdrawn or tapered off whenever possible to prevent adrenal insufficiency.
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