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Dissolving Acetylcysteine 600 mg effervescent tablet together with other medicinal products is not recommended.
The inactivation of antibiotics (tetracycline, aminoglycosides, penicillin) by acetylcysteine has been reported up to now only in in vitro tests whereby the relevant substances were mixed directly with each other. However, if oral antibiotics are required, it is advised that these should be administered separately and at an interval of at least 2 hours.
Acetylcysteine may potentiate the vasodilatory effect of nitroglycerine. If concomitant therapy is necessary, caution is required and the patient's blood pressure has to be monitored in terms of hypotension that can become serious.
Activated charcoal can decrease the effect of acetylcysteine due to reduced absorption.
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