Oxalee Adverse Reactions

Infections and infestations: Infection, catheter infection, conjunctivitis, infection with normal absolute neutrophil count (ANC), infection with low ANC, unknown infection, upper respiratory tract infection, pneumonia, gingivitis, septic shock, sepsis.
Neoplasms benign, malignant and unspecified (including cysts and polyps): Aggravated neoplasm malignant.
Blood and lymphatic system disorders: Granulocytopenia, leukopenia, lymphopenia, febrile neutropenia, anemia, neutropenia, thrombocytopenia, hyperbilirubinemia, hemolytic anemia, immune-mediated thrombocytopenia, immune-allergic hemolytic anemia, hemolysis, neutropenic sepsis.
Immune system disorders: Allergy/allergic reaction, anaphylactic reactions (including bronchospasm, angioedema, hypotension, sensation of chest pain, and anaphylactic shock), urticaria, hypersensitivity, allergic rhinitis, optic neuritis, Guillain-Barre syndrome.
Metabolism and nutrition disorders: Edema, anorexia, hypokalemia, dehydration, metabolic acidosis, hyperglycemia, hypocalcemia, hyponatremia, hypomagnesemia, peripheral edema.
Psychiatric disorders: Throat tightness, dysphasia, insomnia, depression, anxiety, nervousness, somnolence, dysarthria.
Nervous system disorders: Overall peripheral sensory neuropathy, headache, dysgeusia, sensory disturbance, paresthesia, dizziness, vertigo, muscle weakness, involuntary muscle contractions/fasciculation, intracerebral hemorrhage, loss of deep tendon reflexes, Lhermitte's sign, cranial nerve palsies, convulsion, posterior reversible encephalopathy syndrome (PRES), decrease of visual acuity, neuralgia, cranial nerve dysfunction (including ptosis, diplopia, aphonia, dysphonia, hoarseness, sometimes described as vocal cord paralysis, abnormal tongue sensation/dysarthria, sometimes described as aphasia, trigeminal neuralgia, facial pain, fasciculation, eye pain, decrease of visual acuity, visual field disturbance, transient blindness, amaurosis and amaurosis fugax), jaw spasm, myoclonus, abnormal coordination, abnormal gait, balance disorders.
Eye disorders: Abnormal lacrimation, visual impairment/abnormal vision, visual field disturbance, transient vision loss, tearing.
Ear and labyrinth disorders: Deafness.
Cardiac disorders: Chest tightness, chest pain, tachycardia, dyspnea, ventricular arrhythmia, Torsades de Pointes.
Vascular disorders: Epistaxis, hemorrhage, flushing, deep vein thrombosis/deep thrombophlebitis, hypertension, hypotension, thrombosis, syncope, thromboembolism, rectal bleeding, hemorrhoids, hemoptysis, hot flush, anaphylactic shock, sinusoidal obstruction syndrome/veno-occlusive liver disease, tissue necrosis.
Respiratory, thoracic and mediastinal disorders: Pulmonary embolism, rhinitis, cough, pharyngolaryngeal dysesthesia, pneumonitis, hypoxia, pharyngitis, laryngospasm, pulmonary fibrosis, interstitial lung disease, sinusitis.
Gastrointestinal disorders: Abdominal pain, nausea, diarrhea, vomiting, stomatitis, constipation, dyspepsia, hiccups, flatulence, mouth dryness, rectal pain, gastroesophageal reflux disease, melena, proctitis, intestinal obstruction, enlarged abdomen/abdominal distention, gastrointestinal hemorrhage, colitis, ileus, pancreatitis, tenesmus, intestinal ischemia, duodenal ulcer.
Hepatobiliary disorders: Ascites, hypoalbuminemia, hepatotoxicity, perisinusoidal fibrosis, hepatic failure, hepatitis.
Skin and subcutaneous tissue disorders: Skin disorder, alopecia, skin exfoliation (i.e. hand and food syndrome), rash erythematous, rash, nail disorder, pigmentation changes, pruritus, dry skin, hand and foot syndrome, purpura.
Musculoskeletal and connective tissue disorders: Back pain, myalgia, chills/rigors, arthralgia, bone pain, rhabdomyolysis, muscle spasm, muscle twitching.
Renal and urinary disorders: Urinary frequency, increased creatinine, dysuria, hematuria, urinary incontinence, hemolytic-uremic syndrome, acute renal failure, renal tubular necrosis/acute tubular necrosis, acute interstitial nephritis, urinary tract infection.
Reproductive system and breast disorders: Vaginal hemorrhage.
General disorders and administration site conditions: Fatigue, fever, asthenia, pain, hyperhidrosis/sweating, mucositis, ataxia, extravasation.
Investigations: Weight increase, weight decrease, alkaline phosphatase increased, prolonged prothrombin time and International Normal Ratio (INR), increased transaminases, increased hepatic enzymes, blood bilirubin increased, blood lactate dehydrogenase increased, QT prolongation, decreased neutrophils.
Injury, poisoning and procedural complications: Injection site reaction (redness, swelling, pain), accidental injury, phlebitis, contusion/bruise.
Surgical and medical procedures: Diarrhea-colostomy.