Oncef Side Effects

Shock: As a shock may rarely occur, cautious monitoring is required, and in case that unpleasantness, stridor, dizziness, tenesmus tinnitus, etc. occur, administration should be discontinued and appropriated should be taken.
Hypersensitivity: In case exanthema, urticaria, erythema, flare, pruritus, shivering, fever, allergic dermatitis, edema, erythema multiforme, anaphylactic or anaphylactic-like reaction occur, further administration should be discontinued and appropriate measures taken.
Blood: Occasionally granulocytopenia, eosinophilia, thrombocytosis, leukopenia, rarely anemia, hemolytic anemia, thrombocytopenia, prothrombin abnormality may occur.
Liver: Occasionally elevation of AST, ALT, ALP, and symptomatic precipitation ceftriaxone calcium salt in the gall-bladder rarely elevation of bilirubin. GPT may occur.
Kidney: As severe renal disorder such as an acute renal insufficiency is reported rarely, cautious monitoring is required and if abnormality acknowledged further administration should be discontinued and appropriate measures taken.
GI System: Rarely severe enterocolitis with hemafecia such as pseudomembranous enterocolitis may occur. If abdominal pain and frequent diarrhea occur, appropriate measures such as immediate discontinuation of ceftriaxone should be taken. Also occasionally nausea, vomiting, loose tools, diarrhea or rarely abdominal pain, anorexia, etc. may occur.
Respiratory system: Since interstitial pneumonia, PIE syndrome, etc. accompanied with fever, cough, dyspnea, abnormal chest x-ray, eosinophilia, etc. may rarely occur with other cephems. In case that such symptoms occur further administration should be discontinued and appropriate measures such as administration of corticosteroids. etc should be taken.
Superinfection: Rarely stomatitis, candidiasis may occur.
Vitamin deficiency: Rarely symptoms of vitamin K deficiency (hypoprothrombinemia, hemorrhage tendency, etc.) and vitamin B deficiency (glossitis, stomatitis, anorexia, neuritis, etc.) may occur.
Others: Occasionally headache and rarely dizziness, edema, precipitation in gallbladder, ventricular extrasystole, elevated creatinine of blood, genital mycosis may occur.