Numetrax Special Precautions

In order to prevent appearance of the resistant microorganisms, susceptibility should be determined and treatment should be continued only for the minimum period of time required.
In order to predict adverse reaction such as shock, etc. patient history should be taken in detail and skin reaction test should be performed.
Emergency measures have to be available in preparation for occurrence of shock (if anaphylactic shock occurs, intravenous epinephrine has to be followed by a glucocorticoid injection), and even after measures taken the patient should be observed cautiously in stable condition.
It is desirable to perform laboratory test ( hepatic function, renal function, blood etc.) at regular intervals during treatment.
Shadows which have been mistaken for gallstone have been detected on sonograms of the gallbladder, usually following doses higher than the standard recommended dose. These shadows are, However, precipitates of ceftriaxone calcium which disappear on completion or discontinuation of its therapy. Rarely, these findings have been associated with symptoms. In symptomatic cases, conservative non-surgical management is recommended. Discontinuation of its treatment in symptomatic cases should be at the discretion of the clinician.
In the case of overdosage, drug concentration would not be reduced by hemodialysis or peritoneal dialysis. There is no specific antidote. Treatment of overdosage should be symptomatic.
It is not reported to have adverse effect on a person's ability to drive vehicles or operate machinery.
Careful administrations: Patients with history of drug allergy.
Patients oneself or whose parents, sisters or brothers are prone to suffer from allergic symptoms such as bronchial asthma, exanthema, urticarial, etc.
Patients with severe renal disorder (as the plasma concentration is maintained for a long period of time, decreased dosage or increased interval between treatments are required.
Patients with poor oral or parenteral nutrition patients, elderly patients, patients with poor general conditions (cautious monitoring is required since Vitamin K deficiency may occur).