Lupinsulin 30:70 Caution For Usage

Injection Technique: Correct Syringe: The dose of insulin is always expressed in international units (IU). Please study the markings made on the insulin syringe carefully and understand the calculation of the dose in mL. Make sure that only a syringe calibrated to 40 and/or 100 IU/mL. The volume of insulin to be injected depends upon the dose required by the patient. Use a syringe marked for the insulin. If proper syringe is not used, it may lead to an error in the dosage. These may cause serious problems eg, blood glucose may become too low or too high.
Sterilization of Insulin Syringes: Do not share the syringe or needle with anyone else. Reusable syringe and needles must be sterilized before each injection. Separate the syringe, plunger (piston) and needle. Place them in water in a covered container.
Bring the water to boiling and continue to boil for at least 5 min. Allow it to cool completely. Disposable syringe and needle are used only once and then discard.
Preparing the Dose and Injection: Wash hands with soap and water.
Insert the plunger into the syringe; fix the needle with a slight twist. Push the plunger in and out several times to remove all the water that might have remained inside. The syringe is ready for use. However, this step is not necessary while using a sterile disposable syringe and a needle. Gently rotate the insulin vials several times to ensure that the contents are properly mixed. Insulin should have a uniform milky appearance. Do not use the insulin if anything unusual is detected in the appearance of the vial.
When using a new vial, remove the plastic protective cap on the stopper. However, do not remove the stopper.
Wipe the top of the vial with a spirit swab immediately before drawing insulin into the syringe and allow it to dry.
If the physician has advised the patient to mix different types of insulin, ensure to follow the same sequence for drawing insulin from the vials every time. The insulin mixture should be prepared just prior to injection.
Pull the plunger down to the required mark and draw air into the syringe equivalent to the volume of insulin to be withdrawn for administration. Push the needle through the rubber stopper into the vial and inject the air into the vial. Please note that it will be difficult to draw insulin into the syringe unless an equal volume or at least ½ of the required volume of air is injected into the vial. Ensure that the tip of the needle is in insulin and then invert the vial along with the needle and the syringe and draw the required dose of insulin.
Pull the needle out of the insulin vial. If there are any air bubbles in the syringe, hold the syringe vertical with the needle on top and gently tap the syringe. It will make the air bubbles move towards the needle. Remove the air bubble by pushing the plunger slowly. Check that the correct dose of insulin has been drawn into the syringe.
Other Information: The vials of insulin zinc, isophane insulin human and insulin human + isophane insulin human preparations should look uniformly milky after mixing. Do not use if the white material remains at the bottom of the vial after mixing. If anything unusual is noticed in the appearance of the vial of insulin or noticed that the insulin requirements are changing frequently, consult the physician immediately.