Linzowel Mechanism of Action

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Action

Pharmacology: Pharmacokinetics: Linezolid is rapidly and extensively absorbed after oral doses and maximum plasma concentrations are achieved after 1 to 2 hours. It is about 31% bound to plasma proteins. Linezolid is reported to be distributed into bone, fat, lungs, muscle, skin blister fluids, and into CSF. It is metabolised mainly by oxidation to 2 main inactive metabolites, the hydroxyethyl glycine metabolite (PNU-142586) and the aminoethoxyacetic acid metabolite (PNU-1423000) other minor inactive metabolites have also been identified. About 40% of a dose is excreted in the urine as PNU-142586, 30% as Linezolid, and 10% as PNU-142300. Small amounts of metabolite are excreted in the feces. The elimination half-life of Linezolid is about 5 to 7 hours.

linezolid

Manufacturer:

Innova Captab

Distributor:

Uni-Pharma

Marketer:

Ambica