Levox Use In Pregnancy & Lactation

Use in Pregnancy: Category C. In the absence of human data and due to the experimental risk of damage by fluoroquinolones to the weight-bearing cartilage of the growing organism, Levofloxacin solution for infusion must not be used in pregnant and lactating women.
750 mg Infusion: (Pregnancy Category C). There are no adequate and well-controlled studies using levofloxacin in pregnant women. Since levofloxacin, as with most other fluoroquinolones, causes arthropathy in immature animals, the drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus (see Precautions).
Use in Lactation: Levofloxacin has not been measured in human milk. Based upon Ofloxacin data, it can be presumed that Levofloxacin will be excreted in human milk. Because of the potential for serious adverse reactions from Levofloxacin in nursing infants, decide whether to discontinue drug or discontinue nursing, taking into account the importance of the drug to the mother.
750 mg Infusion: Levofloxacin has not been measured in human milk. However, based on the ofloxacin data, it can be presumed that levofloxacin will be excreted in human milk. Therefore, a decision should be made whether to discontinue breastfeeding or to discontinue the drug, taking into account the importance of the drug to the mother as well as the possible serious adverse effects to the infant.