Levox Drug Interactions

Tablet: Antacids, sucralfate, metal cations, and zinc-containing multivitamin preparations may interfere with the gastrointestinal absorption of Levofloxacin resulting in systemic levels considerably lower than desired.
Vial: There are no data concerning an interaction of Levofloxacin I.V. with oral antacids, sucralfate, multivitamins, didanosine, or metal cations. However, do not co-administer quinolone with any solution containing multivalent cations, e.g., magnesium, through the same intravenous line.
Theophylline, fenbufen or similar non-steroidal anti-inflammatory drugs: No pharmacokinetic interactions of Levofloxacin are found with Theophylline. However, there are indications of a pronounced lowering of the cerebral seizure threshold when quinolones are given concurrently with other drugs that lower the seizure threshold or with Fenbufen or similar non-steroidal anti-inflammatory drugs.
Interference with Laboratory Tests: Levofloxacin may inhibit the growth of Mycobacterium tuberculosis, and therefore, may give false-negative results in the bacteriological diagnosis of tuberculosis.
750 mg Infusion: See Table 6.

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