Konakion MM Use In Pregnancy & Lactation

Pregnancy, nursing mothers: No controlled studies of Phytomenadione (Konakion) have been performed in animals or pregnant women. On the basis of many years' clinical experience, however, it is safe to assume that neither vitamin K₁ nor the excipients contained in the Phytomenadione (Konakion) formulations have any reproductive toxicological effects when the drug is given at the recommended dosages. As with all medications, however, Phytomenadione (Konakion) should be given to pregnant women only if the benefit to the mother outweighs the risk to the fetus.
As vitamin K₁ does not readily cross the placental barrier, it is not recommended that Phytomenadione (Konakion) be given to expectant mothers as prophylaxis of hemorrhagic disease in the newborn.
Only a small fraction of administered vitamin K₁ enters the breast milk. At therapeutic doses, administration of Phytomenadione (Konakion) to nursing mothers accordingly does not pose a risk to their infants.
However, Phytomenadione (Konakion) is not recommended for nursing mothers as prophylaxis of hemorrhagic disease in the newborn.