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Hemorrhage or risk of hemorrhage as a result of severe 'hypoprothrombinemia' (i.e. deficiency of clotting factors II, VII, IX and X) of various etiologies, including overdosage of coumarin-type anticoagulants, their combination with phenylbutazone and other forms of hypovitaminoses K (e.g. in obstructive jaundice as well as liver and intestinal disorders, and after prolonged treatment with antibiotics, sulfonamides or salicylates).
For prophylaxis and treatment of hemorrhagic disease in the newborn, Phytomenadione (Konakion) MM pediatric ampoules (2 mg/0.2 mL) should be used.
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