Isordil Indications/Uses

Angina Pectoris: Isosorbide dinitrate Oral Tablets: For prophylaxis of ischemic heart pain associated with coronary insufficiency. Isosorbide dinitrate may reduce the frequency, duration and severity of angina attacks. Exercise tolerance may be improved and the need for nitroglycerin may be reduced. The oral tablets are not indicated for the treatment of an angina attack.
Isosorbide dinitrate Sublingual Tablets: For treatment of angina pectoris and for prophylaxis in situations likely to provoke an angina attack i.e. physical or emotional stress.
Congestive Heart Failure: Acute and chronic congestive heart failure (including that associated with myocardial infarction). Based on current knowledge, isosorbide dinitrate should be considered only as an adjunct to the more conventional modes of therapy (cardiac glycosides and diuretics); however, in refractory cases, it may be used alone or concomitantly with other vasodilators. Isosorbide dinitrate is particularly effective in patients with increased left ventricular end diastolic pressure (LVEDP) - "backward failure" - and normal or approximately normal cardiac output in whom pulmonary congestion or edema is the primary problem. Isosorbide dinitrate is especially recommended when coronary artery disease is the cause of congestive heart failure, in which case its anti-anginal effect of additional value.