menu Search
Hypace

Hypace Use In Pregnancy & Lactation

enalapril

Manufacturer:

Pascual Pharma Corp

Distributor:

Pascual Pharma Corp
Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing
Full Prescribing Info
Use In Pregnancy & Lactation
Use in lactation: Following administration of a single dose of enalapril 20 mg to 5 lactating women, enalaprilat was detected in breast milk in concentrations of 1-2.3 ng/mL (mean peak 1.72 ng/mL). This was compared with peak serum values of 39-112 ng/mL for enalaprilat and 92-151 ng/mL for enalapril. Although enalapril and its metabolite are present in small amounts in breast milk, it was calculated that the average total daily dose to the neonate would only be about 2 mcg of enalaprilat.