Gracefix Dosage/Direction for Use

Usual Course of Treatment: 5-14 days.
Adults and Children >12 years: Recommended Dose: 400 mg daily as single dose.
Children <12 years: Recommended Dose: 8 mg/kg/day as a single daily dose or may be given in 2 divided doses.
As a general guide for prescribing in children, the following daily doses are suggested: Children 10-12 years: 15 mL daily; 5-9 years: 10 mL daily; 1-4 years: 5 mL daily.
Infants 6 months-1 year: 3.37 mL daily.
The dosage in children 6 months-1 year should be calculated on mg/kg basis. The safety and efficacy of cefixime has been established in children <6 months.
Elderly: Elderly may be given the same dose as recommended for adults. Renal function should be assessed and dosage should be adjusted in severe renal impairment.
Renal Impairment: Cefixime may be adjusted in the presence of impaired renal function. Normal dose and frequency may be given in patients with creatinine clearance (CrCl) of ≥20 mL/min. It is recommended that a dose of 200 mg once daily should not be exceeded. The dose and regimen for patients who are maintained on chronic ambulatory peritoneal dialysis or hemodialysis should follow the same recommendation as that for patients with CrCl <20 mL/min.