Geotrixx Dosage/Direction for Use

Injection: ADULTS: The usual adult daily dose is given 1 to 2 grams by IM or IV once a day (or in equally divided doses twice a day) depending on the type and severity of infection.
The total daily dose should not exceed 4 grams.
NEONATES (under 14 days from birth): The recommended dose of is 20 to 50 mg/kg/day once a day and the dose should not exceed 50 mg/kg/day.
INFANTS & CHILDREN UNDER 12 YEARS OLD: The recommended dose is 20 to 80 mg/kg/day once a day. When the dose was given over 50 mg/kg, it should be administered intravenously by infusion over a period of 30 minutes.
ELDERLY PEOPLE: The usual dose is same with for adults.
In the treatment of meningitis, it is recommended that the initial therapeutic dose be 100 mg/kg (not to exceed 4 grams). Thereafter, a total daily dose of 100 mg/kg/day (not to exceed 4 grams daily) is recommended. The daily dose may be administered once a day (or in equally divided doses every 12 hours).
Effective duration of therapy: See Table 1.

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For the treatment of uncomplicated gonococcal infections, a single intramuscular dose of 250 mg is recommended.
For preoperative use (surgical prophylaxis), a single dose of 1-2 grams administered intravenously to 2 hours before surgery is recommended.
No dosage adjustment is necessary for patients with impairment of renal or hepatic function, however, blood levels should be monitored in patients with severe renal impairment (eg, dialysis patients) and in patients with both renal and hepatic dysfunctions. In patients with estimated creatinine clearance of less than 10 mL/min, total daily dose should not exceed 2 grams.
Duration of therapy: Generally, ceftriaxone therapy should be continued for at least 48-72 hours after the signs and symptoms of infection have disappeared.