Fosfostal Dosage/Direction for Use

One sachet (3 g of active substance), single dose regimen.
Clinical symptoms usually disappear 2-3 days after beginning of treatment.
In acute infections of the lower urinary tract (cystitis, nongonococcal urethritis) caused by microorganisms susceptible to Fosfomycin, a single dose (3 g of active substance in adults) is sufficient for recovery. The persistence of local symptoms, if any, after treatment, is not necessarily a sign of therapeutic failure, but usually the consequence of the past inflammation.
In more clinically problematic cases (elderly, bedridden patients, recurrent infections) or in infections due to microorganisms usually susceptible to the highest antibiotic doses (Pseudomonas, Enterobacter, Indole Proteus) two Fosfomycin doses can be administered at a 24-hr interval.
Fosfomycin should be taken on an empty stomach or about 2-3 hours after meals, preferably before bedtime and after emptying the bladder. The dose must be dissolved in a glass of water (50-75 mL) or in another favorite non-alcoholic drink and administered soon after dissolving.