Duomax is not recommended for initial therapy of tuberculosis or for prevention therapy.
Duomax should be used with caution in patients of diabetes mellitus, since diabetes management may be more difficult.
Rifampicin: Intermittent administration (once or twice weekly) of rifampicin may cause flu-like syndrome with fever, chills and malaise, hematologic reactions (leukopenia, thrombocytopenia or acute hemolytic anemia), cutaneous and hepatic reactions more frequently. Duomax due to its rifampicin content, may produce a reddish coloration of the urine, sweat, sputum and tears about which the patient should be cautioned.
Isoniazid: Patients who consume alcohol daily should be carefully monitored for hepatitis.
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