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Patients receiving cefaclor may show a false-positive reaction for glucose in the urine with tests that use Benedict's and Fehling's solutions and also with Clinitest tablets but not with Tes-Tape (Glucose Enzymatic Test Strip, USP, Lilly).
There have been rare reports of increased anticoagulant effect when cefaclor and oral anticoagulants were administered concomitantly.
There have been rare reports of increased prothrombin time with or without clinical bleeding in patients receiving cefaclor and coumadin concomitantly. (See Adverse Reactions).
As with other β-lactam antibiotics, the renal excretion of cefaclor is inhibited by probenecid.
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