Ceclor/Ceclor DS Dosage/Direction for Use

Cefaclor is administered orally.
Adults: The usual adult dosage is 250 mg every 8 hours. For bronchitis and pneumonia, the dosage is 250 mg administered 3 times daily. A dosage of 500 mg administered 3 times daily for 10 days is recommended for sinusitis. For more severe infections (such as pneumonia) or those caused by less susceptible organisms, doses may be doubled. Doses of 4 g/day have been administered safely to normal subjects for 28 days, but the total daily dosage should not exceed this amount.
For the treatment of acute gonococcal urethritis in males and females, a single dose of 3 g combined with probenecid, 1 g, is given.
Children: The usual recommended daily dosage for children is 20 mg/kg/day in divided doses every 8 hours. For bronchitis and pneumonia, the dosage is 20 mg/kg/day in divided doses administered 3 times daily. In more serious infections, sinusitis, otitis media, and infections caused by less susceptible organisms, 40 mg/kg/day in divided doses are recommended, with a maximum dosage of 1 g/day. (See Table 5.)

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Cefaclor may be administered in the presence of impaired renal function.
Under such a condition, the dosage usually is unchanged (see Precautions). In the treatment of β-hemolytic streptococcal infections, a therapeutic dosage of cefaclor should be administered for at least 10 days or as prescribed by the physician.
Directions for Reconstitution: Ceclor 50 mg/mL Granules for Suspension (Oral Drops): To make a 20 mL suspension, slowly add 12 mL of water. Replace cap and shake well.
Ceclor 125 mg/5 mL Powder for Suspension and Ceclor DS 250 mg/5 mL Powder for Suspension: To make a 60 mL suspension add 36 mL water in two portions. Replace cap and shake well after each addition. The reconstituted suspension will retain its potency for 14 days when kept in a refrigerator (2-8°C).