Ceclor/Ceclor DS: Side Effects & Dosing

Indications/Uses

Resp tract infection including pneumonia, pharyngitis/tonsillitis & sinusitis. Skin & skin structure infections; UTI including pyelonephritis & cystitis. Otitis media, gonococcal urethritis.

Dosage/Direction for Use

Adult Usual dose: 250 mg every 8 hr. Bronchitis & pneumonia 250 mg tid. Sinusitis 500 mg tid for 10 days. More severe infection (eg, pneumonia) or infection caused by less susceptible organisms Dose may be doubled. Max: 4 g/day. Acute gonococcal urethritis 3 g as a single dose combined w/ probenecid 1 g. Childn Recommended dose: 20 mg/kg/day in divided doses every 8 hr. Bronchitis & pneumonia 20 mg/kg/day in divided doses tid. Serious infection, sinusitis, otitis media & infection caused by less susceptible organisms 40 mg/kg/day in divided doses. Max: 1 g/day.

Administration

May be taken with or without food.

Contraindications

Hypersensitivity to cephalosporins.

Special Precautions

Penicillin-sensitive patients. Cross-hypersensitivity. Superinfection. History of GI disease. Renal impairment. +ve Coombs' test. Pregnancy & lactation.

Adverse Reactions

Serum sickness-like reactions, SJS, TEN. Diarrhea symptoms of pseudomembranous colitis, eosinophilia, genital pruritus or vaginitis, moniliasis, angioedema. Slight elevations of SGOT, SGPT or alkaline phosphatase & BUN. Transient lymphocytosis & leukopenia.

View ADR Reporting Link

Drug Interactions

Concomitant use w/ probenecid or oral anticoagulants.

MIMS Class

Cephalosporins

ATC Classification

J01DC04 - cefaclor ; Belongs to the class of second-generation cephalosporins. Used in the systemic treatment of infections.

Regulatory Classification

Rx

Presentation/Packing

Form

Ceclor granules for susp 50 mg/mL

Packing/Price

20 mL x 1's

Form

Ceclor DS powd for susp 250 mg/5 mL

Packing/Price

60 mL x 1's

Form

Ceclor powd for susp 125 mg/5 mL

Packing/Price

60 mL x 1's

Ceclor/Ceclor DS

cefaclor

Manufacturer:

Aspen

Distributor:

Distriphil