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When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. When pregnancy is detected, Losartan Potassium should be discontinued as soon as possible.
Should be used with care in pregnancy and during breast feeding, since the act on the renin-angiotensin system have been associated with fetal toxicity in humans.
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