Arbloc Indications/Uses

Losartan Potassium is an angiotensin II receptor antagonist with an antihypertensive activity due mainly to selective blockade of AT₁ receptors and the consequent reduced pressor effect of angiotensin II.
Hypertension: Losartan Potassium is used in the management of hypertension alone or in combination with other antihypertensive agents and may have a role in patients who develop cough with ACE inhibitors.
Hypertensive patients with left ventricular hypertrophy: Losartan Potassium is indicated to reduce the risk of stroke, heart failure and myocardial infarction in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to black patients.
Nephropathy in type 2 diabetic patients: Losartan Potassium is also indicated in the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio greater than or equal to 300 mg/g) in patients with type 2 diabetes and a history of hypertension. In this population, Losartan reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end renal disease (need for dialysis or renal transplantation).