Pregnancy: Capsule: Excessive doses of preformed vitamin A are teratogenic, as may be marked maternal deficiency. In addition, recent evidence has demonstrated that severe maternal vitamin A deficiency may increase the risk of mother-to-child HIV transmission and reduced infant growth during the first year.
The recommended dietary allowance (RDA) of vitamin A for normal pregnant women is 900 IU, and the tolerable upper limit intake (UL) is 2800-3000 IU. Because of the teratogenic effects secondary to excessive vitamin A intake, the WHO recommends as safe during pregnancy a maximum dose of up to 10,000 IU daily or 25,000 IU weekly after the first 60 days of gestation.
The recommended dietary allowance (RDA) of vitamin D for normal pregnant women is 400 IU, and the tolerable upper limit intake (UL) is 2000-4000 IU. Large doses of vitamin D should not be used during pregnancy unless the clinical condition of the woman requires treatment with cholecalciferol, at a dose necessary to overcome the deficiency.
Based on human experience and animal studies, vitamin D overdose causes physical and mental disability and congenital heart and eye conditions, due to hypercalcemia, when administered during pregnancy.
Clinical data with use of buclizine in humans are not adequate to establish safety during pregnancy. Although experiments in some animals gave rise to adverse effects following the administration of buclizine to pregnant animals.
Lactation: Capsule: Vitamins A and B are expressed in breastmilk. Very large doses of vitamin B6 have been reported to suppress lactation.
Cholecalciferol (vitamin D) and its metabolites are excreted in breastmilk. Overdose in infants induced by nursing mothers has not been observed. However, when prescribing additional vitamin D to a breast-fed child, the practitioner should consider the dose of any additional vitamin D given to the mother.
Maternal dietary iron appears to have little effect on human milk iron concentration.
Due to the limited safety information of this product during pregnancy and lactation, consider using this product only if the benefit outweighs the risk.
Other Services
Country
Account