Appetite With Iron Drug Interactions

Capsule: Retinol (Vitamin A): Contraceptive pills raise the plasma levels of Vitamin A.
Chronic excessive alcohol consumption increases the risk of vitamin A hepatotoxicity.
Neomycin can markedly reduce the absorption of vitamin A from the gut.
Long-term use of vitamin A or taking high doses may increase the risk of bleeding for those taking blood-thinning medications, particularly warfarin.
Simultaneous treatment with ion exchange resins such as cholestyramine or laxatives such as paraffin oil may reduce the gastrointestinal absorption of the vitamin.
Cholecalciferol (Vitamin D₃): Vitamin D increases calcium gastrointestinal absorption.
Vitamin D should not be given in patients taking the following: paricalcitol, calcipotriene, doxercalciferol, mineral oil, orlistat, and bile acid sequestrants like colesevelam, colestipol, cholestyramine.
Co-administration of benzothiadiazine derivatives (thiazide diuretics) increases the risk of hypercalcemia because they decrease the calcium excretion in the urine. The calcium levels in plasma and urine should therefore be monitored for patients undergoing long-term treatment.
Anticonvulsants such as phenytoin, phenobarbital, primidone may diminish the effect of cholecalciferol due to hepatic enzyme induction.
Thiamine (Vitamin B₁): Fluorouracil increases thiamin metabolism and block the formation of thiamine pyrophosphate that could further exacerbate pre-existing thiamine deficiency in cancer patients.
Pyridoxine (Vitamin B₆): Vitamin B₆ reduces the effects of levodopa, but this does not occur if a dopa decarboxylase inhibitor is also given.
High doses of vitamin B₆ can decrease serum concentration of phenytoin and phenobarbital.
Vitamin B₆ can reduce the effectiveness of altretamine (hexamethyl melamine).
Cyanocobalamin (Vitamin B₁₂): Aspirin, proton pump inhibitors, H2-receptor antagonists, neomycin, and colchicine can reduce the absorption of vitamin B₁₂ from the gut.
Intake of chloramphenicol may cause a milder, reversible bone marrow depression which can oppose the treatment of anemias with vitamin B₁₂.
Ferrous sulfate (Iron): The absorption of iron and the expected hematological response to iron can be reduced by the concurrent use of antacids.
Beverage high in polyphenolics may reduce iron absorption.
Intake of chloramphenicol may cause a milder, reversible bone marrow depression which can oppose the treatment of anemias with iron.
Neomycin may alter the absorption of iron.
Iron reduces the absorption of penicillamine, tetracycline, cefdinir, methyldopa, levodopa, quinolone antibiotics (ciprofloxacin, ofloxacin, norfloxacin and moxifloxacin) and levothyroxine through chelate formation.
Buclizine: Buclizine may enhance the sedative effect of nervous depressants including alcohol, barbiturates, hypnotics, narcotics, analgesic, sedatives, and tranquilizers.
Syrup: Consult the doctor first if the patient is taking fluorouracil, levodopa, anticonvulsants, altretamine, aspirin, proton pump inhibitors, H2-receptor antagonists, neomycin, colchicine, chloramphenicol, antacids, penicillamine, tetracycline, cefdinir, methyldopa, quinolone antibiotics, levothyroxine, and nervous depressants like alcohol, barbiturates, hypnotics, narcotics, analgesic, sedatives, and tranquilizers.
Avoid drinking coffee, tea, or red wine while taking this medicine.