Strepsils Max Pro Lozenge Mechanism of Action

Pharmacotherapeutic Group: Other throat preparations, throat preparations. ATC Code: R02AX01.
Pharmacology: Pharmacodynamics: Flurbiprofen is a non-steroidal anti-inflammatory drug which has potent analgesic, antipyretic and anti-inflammatory properties which are thought to result from the drug's ability to inhibit prostaglandins synthesis.
The onset of pain relief, reduction in throat soreness and reduction in throat swelling was observed 30 minutes after taking a lozenge and duration of action extended 2-3 hours.
Pharmacokinetics: Flurbiprofen is rapidly absorbed following the use of Strepsils Max Pro Honey & Lemon 8.75 mg Lozenge with plasma concentrations peaking at 30-40 minutes. Peak concentrations are achieved more rapidly than, but are if similar magnitude to, those achieved after an equivalent swallowed dose.
Flurbiprofen is rapidly distributed throughout the body. It is mainly metabolized by hydroxylation and excreted via the kidneys.
It is extensively bound to plasma proteins and has an elimination half-life of 3-6 hours.
Flurbiprofen is excreted in very small amounts in human milk (less than 0.05 μg/mL).