Hypersensitivity to flurbiprofen, aspirin, other NSAIDs, other lozenge ingredients or any of the excipients in the product.
Patients who have previously shown hypersensitivity reactions (e.g. bronchospasm, asthma, rhinitis, angioedema, or urticaria) in response to aspirin or other non-steroidal anti-inflammatory drugs.
Existing or history of peptic ulcerations/haemorrhage (two or more distinct episodes of proven ulceration or bleeding).
History of gastrointestinal bleeding or perforation, related to previous NSAIDs therapy.
Severe heart failure, renal failure or hepatic failure (see Precautions).
Last trimester of pregnancy.