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Klacid Hp

Klacid Hp Adverse Reactions

amoxicillin

pantoprazole

clarithromycin

Manufacturer:

Abbott

Distributor:

Zuellig Pharma
Full Prescribing Info
Adverse Reactions
Klacid: Clarithromycin is generally well tolerated. Side effects reported include nausea, dyspepsia, diarrhoea, vomiting, taste perversion and abdominal pain. Stomatitis, glossitis and oral monilia have been reported. Other side effects include headache and allergic reactions ranging from rash, urticaria and severe cutaneous adverse reactions (SCAR) (e.g. Acute generalized exanthematous pustulosis (AGEP), Steven-Johnson syndrome, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms (DRESS). There have been reports of transient central nervous system side effects including anxiety, dizziness, insomnia, hallucinations, psychosis, bad dreams and confusion, however, a cause and effect relationship has not been established. There have been reports of hearing loss with clarithromycin which is reversal upon withdrawal of therapy. Pseudomembranous colitis has been reported rarely with clarithromycin, and may range in severity from mild to life threatening. As with other macrolides, hepartic dysfunction (which is usually reversible) including altered liver function tests, hepatitis and cholestasis with or without jaundice, has been reported. Dysfunction may be severe and very rarely fatal hepatic failure has been reported.
Controloc: Treatment with Controloc can occasionally lead to headache, gastrointestinal complaints such as upper abdominal pain, diarrhea, constipation or flatulence and allergic reactions such as pruritus, skin rash (in isolated cases also urticaria or angioedema).
There have been rare reports of nausea, dizziness or disturbances in vision (blurred vision). Peripheral edema, fever, depression or myalgia subsiding after termination of therapy were reported in individual cases.
Microscopic colitis has been included under gastrointestinal disorders with frequency not known while under skin and subcutaneous tissue disorders, there have been report on Stevens-Johnson syndrome; Toxic epidermal necrolysis; Drug reaction with eosinophilia and systemic symptoms; Acute generalized exanthematous pustulosis; Erythema multiforme; Photosensitivity ; Subacute cutaneous lupus erythematosus.
Ospamox: Occasional transient side effects are mostly gastro-intestinal (nausea and diarrhea). Owing to the better absorption of amoxycillin they are, however, less commonly seen than during ampicillin treatment. In patients developing diarrhea during treatment pseudomembranous colitis should be considered. (see also Precautions). Rarely, hypersensitivity reactions like urticarial rashes, fever, joint pain, erythema multiforme, exfoliative dermatitis, angioneurotic edema and hematologic problems,e.g. thrombocytopenia, agranulocytosis, leukopenia and eosinophilia are seen. These usually run a mild course and generally subside within a few days. Like other penicillins, Ospamox may exceptionally cause severe systemic reactions (anaphylactic shock). Exfoliative dermatitis and erytherma multiforme have been described in some cases. Like other penicillins, amoxycillin may cause headache, fatigue, glossitis, stomatitis, fever, joint pain, angioneurotic edema or interstitial nephritis. Minor transient elevations of serum transaminases (SGOT and SGPT) have occasionally been seen.
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