Controloc: Treatment with Controloc can occasionally lead to headache, gastrointestinal complaints such as upper abdominal pain, diarrhea, constipation or flatulence and allergic reactions such as pruritus, skin rash (in isolated cases also urticaria or angioedema).
There have been rare reports of nausea, dizziness or disturbances in vision (blurred vision). Peripheral edema, fever, depression or myalgia subsiding after termination of therapy were reported in individual cases.
Microscopic colitis has been included under gastrointestinal disorders with frequency not known while under skin and subcutaneous tissue disorders, there have been report on Stevens-Johnson syndrome; Toxic epidermal necrolysis; Drug reaction with eosinophilia and systemic symptoms; Acute generalized exanthematous pustulosis; Erythema multiforme; Photosensitivity ; Subacute cutaneous lupus erythematosus.
Ospamox: Occasional transient side effects are mostly gastro-intestinal (nausea and diarrhea). Owing to the better absorption of amoxycillin they are, however, less commonly seen than during ampicillin treatment. In patients developing diarrhea during treatment pseudomembranous colitis should be considered. (see also Precautions). Rarely, hypersensitivity reactions like urticarial rashes, fever, joint pain, erythema multiforme, exfoliative dermatitis, angioneurotic edema and hematologic problems,e.g. thrombocytopenia, agranulocytosis, leukopenia and eosinophilia are seen. These usually run a mild course and generally subside within a few days. Like other penicillins, Ospamox may exceptionally cause severe systemic reactions (anaphylactic shock). Exfoliative dermatitis and erytherma multiforme have been described in some cases. Like other penicillins, amoxycillin may cause headache, fatigue, glossitis, stomatitis, fever, joint pain, angioneurotic edema or interstitial nephritis. Minor transient elevations of serum transaminases (SGOT and SGPT) have occasionally been seen.
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