Prescriber should be informed of any other medicines taken simultaneously by the patient by oral route. Due to the stomach draining provoked by FORTRANS, the other oral treatments may not be absorbed and should be administered more than 2 hours before the draining solution. Avoid intake of oral treatments before and after laxative ingestion until medical examination is completed. For medicines with small therapeutic range or with short half-life such as digoxin, antiepileptics, coumarins, and immunosuppressants, efficacy can be particularly affected.