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Sodium rabeprazole is (±)-sodium 2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl] methylsulfinyl]-1H-benzimidazole. It has a molecular formula of C18H20N3O3S·Na and a molecular weight of 381.43.
Sodium rabeprazole occurs as a white to pale yellowish white powder. It is odorless; very soluble in water and methanol, freely soluble in dehydrated ethanol and ethyl acetate, and practically insoluble in ether and hexane.
Sodium rabeprazole shows no optical rotation. It is hygroscopic. Melting point: 225°C (with decomposition). Partition coefficient: About 214 (pH 7, water-octanol system).
