Active duodenal & benign gastric ulcer; symptomatic erosive or ulcerative GERD. GERD long-term management. Symptomatic treatment of moderate to severe GERD. H. pylori eradication in patients w/ PUD in combination w/ appropriate antibacterial therapeutic regimens.
Active duodenal ulcer 20 mg once daily in the morning for 4-8 wk. Benign gastric ulcer 20 mg once daily in the morning for 6-12 wk. Erosive or ulcerative GERD 20 mg once daily for 4-8 wk. Long-term management (maintenance) of GERD 10 or 20 mg once daily depending on patient's response. Symptomatic treatment of moderate to very severe GERD 10 mg once daily in patients w/o esophagitis. Eradication of H. pylori 20 mg Pariet + clarithromycin 500 mg + amoxicillin 1 g, to be taken twice daily for 7 days.
The possibility of malignancy should be excluded prior to treatment. Long-term treatment should be kept under regular surveillance. Severe hepatic impairment. Cumulative dose should be kept at min. Monitor thyroid function. May impair ability to drive & operate machinery. Childn.
A02BC04 - rabeprazole ; Belongs to the class of proton pump inhibitors. Used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
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