EPODION is contraindicated in patients with: Hypersensitivity to the active substance or to any of the excipients.
Patients who develop pure red cell aplasia (PRCA) following treatment with any erythropoietin should not receive EPODION or any other erythropoietin.
Uncontrolled hypertension.
All contraindications associated with autologous blood predonation programmes should be respected in patients being supplemented with EPODION.
The use of EPODION in patients scheduled for major elective orthopaedic surgery and not participating in an autologous blood predonation programme is contraindicated in patients with severe coronary, peripheral arterial, carotid or cerebral vascular disease, including patients with recent myocardial infarction or cerebral vascular accident.
Surgery patients who for any reason cannot receive adequate antithrombotic prophylaxis.
The use of Epoetin alpha in the indication "to facilitate autologous blood collection" is contraindicated in patients with: Myocardial infarction or stroke in the month preceding treatment; Unstable angina pectoris; Increased risk of deep venous thrombosis such as history of venous thromboembolic disease.
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