Treatment of anemia associated with chronic renal failure in adult patients on haemodialysis and peritoneal dialysis. Treatment of severe anemia of renal origin accompanied by clinical symptoms in adult patients with renal insufficiency not yet undergoing dialysis. Treatment of anemia and reduction of transfusion requirements in adult patients receiving chemotherapy. EPODION can be used to facilitate autologous blood collection within a predeposit programme and decrease the risk of receiving allogenic blood transfusion in patients with moderate anemia (hematocrits of 33-39%, haemoglobin of 10-13 g/dL, [6.2-8.1 mmol/L], no iron deficiency), who are scheduled for major elective surgery and are expected to require more blood than that which can be obtained through autologous blood collection techniques in the absence of Epoetin alfa. EPODION can be used to augment erythropoiesis in the perisurgical period in order to reduce allogeneic blood transfusions and correct postoperative anemia in adult non-iron deficient patients undergoing major elective orthopaedic surgery. Treatment of anemia in symptomatic HIV-infected patients being treated with AZT (Zidovudine) and who are transfusion-dependent.