Pharmacology: EPODION has recombinant human erythropoietin alfa (INN; Epoetin alfa) as an active ingredient, that is a single chain glycoprotein composed of 165 amino acids, and its molecular weight is 26-30 kDa with glycosylation. Epoetin alfa obtained by gene technology is identical in its amino acid sequence to erythropoietin that has been isolated from the urine of anaemic patients. Generally, human erythropoietin is produced in fibroblastoid interstitial cells in the kidneys and liver and then travels to the bone marrow to stimulate red blood cell production. Due to this nature of human erythropoietin, indication of Epoetin alfa is hormone-replacement therapy in the anemia.
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