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Excipients/Inactive Ingredients: Gelatin (Bovine), Ethyl Vanillin, Potassium Sorbate, FDC Yellow #6 (CI 15985), FDC Blue #1 (CI 42090), DC Yellow #10 (CI 47005), Iron Oxide Black (CI 77499), Titanium Dioxide (CI 77891).
Help to fulfill the needs of vitamin A, vitamin C, vitamin E and zinc.
1 soft-capsule once daily or as directed by a doctor.
Missed dose: If the patient missed a dose for the day just take the next dose and subsequent at the usual recommended schedule, i.e., once a day.
Do not double the dose unless recommended by a doctor.
When the patient has taken more than the recommended dosage: If the patient has taken more than the recommended dosage, consult a doctor.
Chronic daily vitamin A intake in excess of 10,000 IU or weekly intakes in excess of 25,000 IU may result in hypervitaminosis A. Excessive vitamin A intake during pregnancy may lead to birth defects such as cleft palate, heart abnormalities, and brain malformations such as hydrocephalus and microcephaly (baby with very small head).
Prolonged intake of vitamin C (>2 grams daily) may lead to nausea, abdominal cramps, diarrhea, and nosebleeds.
Signs of acute zinc toxicity (doses >200 mg daily) include GI pain or cramps, nausea, vomiting, diarrhea, loss of appetite, headache, lethargy, muscle pains, and fever.
When to consult a doctor: If any side effect occurs.
Care that should be taken when taking this medicine: Chronic consumption of vitamin A may cause liver damage.
Vitamin C should use with caution in patients with renal failure because of the risk of kidney stones and patients with deficiency of glucose-6-phosphate dehydrogenase (G6PD) because of the risk of hemolytic anemia, hemochromatosis, sickle cell anemia, thalassemia or sideroblastic anemia.
High doses of vitamin E (doses >100 IU) should be used with caution in patients treated with warfarin, also in patients with a tendency to bleed (e.g.: peptic ulcer), patients with a history of hemorrhagic stroke and patients with a hereditary history of bleeding disorders (e.g.: hemophilia).
Zinc should be used with caution in patients with kidney disease.
If the patient is taking other supplements, read the label, since those supplements may contain the same ingredients as this product.
There are no side effects if the product is used in the recommended dosage.
What other medicine or food should be avoided while taking this medicine: Vitamin A: Anticoagulant (e.g., warfarin): Concomitant administration with large doses of vitamin A may lead to increased risk of bleeding.
Retinoid (e.g., etretinate, isotretinoin, tretinoin): Avoid concomitant use of retinoids and preparations containing vitamin A or its derivatives because of the potential for additive side effects.
Minocycline: Concomitant administration may lead to increased risk of pseudomotor cerebri.
Statin: Prolonged statin treatment may increase serum vitamin A levels.
Vitamin C: Antacids: Concomitant use is not recommended specifically in patients with renal insufficiency since could increase the risk of aluminum toxicity.
Aspirin: Concomitant use may lead to increased urinary excretion of ascorbic acid and decreased excretion of aspirin.
Disulfiram: Prolonged administration of large doses of vitamin C (1 gram daily) may interfere with the alcohol-disulfiram reaction.
Fluphenazine: Concomitant administration with ascorbic acid resulted in decreased fluphenazine plasma level.
Mexiletine: Large doses of ascorbic acid (1 gram daily) of ascorbic acid may accelerate excretion of mexiletine.
Paracetamol: Ascorbic acid increases the apparent half-life of paracetamol.
Oral contraceptives (containing estrogen): These may reduce blood levels of ascorbic acid; large doses of vitamin C (>1 gram) may increase plasma estrogen levels; possibly breakthrough bleeding associated with withdrawal of high dose of vitamin C.
Warfarin: Ascorbic acid has reportedly decreased the anticoagulant effect of warfarin.
Others: Acidification of the urine following ascorbic acid administration may result in altered excretion of other drugs.
Vitamin E: Anticoagulant: Vitamin E reportedly may have anti-vitamin K effects; concomitant intake of anticoagulants (e.g., warfarin) and vitamin E may result in hemorrhage (bleeding).
Antiplatelets: High doses of vitamin E may also potentiate the effects of antiplatelets (e.g., aspirin, clopidogrel, ticlopidine) and herbs with anti-thrombotic activity such as garlic and ginkgo.
Zinc: Antibiotics (cephalosporins, quinolones, tetracyclines): Zinc decreases the absorption of these antibiotics. Taking the antibiotic at least 2 hours before or 4 to 6 hours after taking zinc supplement minimizes this interaction.
Bisphosphonate (alendronate, etidronate, risedronate): Concomitant intake of a bisphosphonate and zinc may decrease the absorption of both the bisphosphonate and zinc.
Cholesterol medicines: Additive effects are possible with concomitant administration. Use with caution.
Copper or iron: Concomitant administration with zinc inhibits the absorption of copper and iron. Administer zinc and copper or iron as far apart as possible.
Interference with Laboratory Test: Vitamin C interferes with the results of the following laboratory tests: Paracetamol, aspartate aminotransferase, bilirubin, carbamazepine, creatinine, glucose, lactate dehydrogenase, stool guaiac, theophylline and uric acid.
Store at temperature below 30°C.
Keep the product out of heat, light and moisture.
A11AA04 - multivitamins and trace elements ; Belongs to the class of multivitamins with minerals. Used as dietary supplements.
Conzace DV softcap
6 × 5's (Rp112,500/boks)