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Conzace DV

Conzace DV

Manufacturer:

Darya-Varia
Concise Prescribing Info
Contents
Vit A 5,000 IU, vit E 100 IU, vit C 500 mg, Zn sulfate 25 mg
Indications/Uses
Helps to fulfill the needs of vit A, C, E, & Zn.
Dosage/Direction for Use
Administration
Should be taken with food.
Contraindications
Pregnancy.
Special Precautions
Vit A: Chronic consumption may cause liver damage. Vit C: Patients w/ renal failure (risk of kidney stones); G6PD deficiency (risk of hemolytic anemia, hemochromatosis, sickle cell anemia, thalassemia or sideroblastic anemia). Interferes w/ lab test results (eg, paracetamol, AST, bilirubin, carbamazepine, creatinine, glucose, LDH, stool guiac, theophylline & uric acid). Vit E: Patients treated w/ warfarin; tendency to bleed (eg, peptic ulcer); w/ history of hemorrhagic stroke & hereditary history of bleeding disorders (eg, hemophilia). Zn: Patients w/ kidney disease.
Adverse Reactions
Nausea, GI pain/abdominal cramps, diarrhea. Vit A: Hypervitaminosis A. Vit C: Nose bleeding. Zn: Vomiting, loss of appetite, headache, lethargy, muscle pain, fever.
Drug Interactions
Vit A: Increased risk of bleeding w/ anticoagulants (eg, warfarin). Potential additive side effects w/ retinoid (eg, etretinate, isotretinoin, tretinoin). Increased risk of pseudomotor cerebri w/ minocycline. Increased serum levels w/ statins. Vit C: Increased risk of Al toxicity w/ antacids, specifically in patients w/ renal insufficiency. Concomitant use w/ aspirin may increase urinary excretion of ascorbic acid & decrease excretion of aspirin. May interfere w/ alcohol-disulfiram reaction. Decreased fluphenazine plasma level. May accelerate excretion of mexiletine. Increases apparent t½ of paracetamol. Reduced blood levels w/ OCs containing estrogens. Decreased anticoagulant effect of warfarin. May result in altered excretion of other drugs. Vit E: May have anti-vit K effects; hemorrhage in concomitant w/ anticoagulants (eg, warfarin). May potentiate the effects of antiplatelets (eg, aspirin, clopidogrel, ticlopidine) & herbs w/ antithrombotic activity eg, garlic & ginkgo. Zn: Decreases absorption of antibiotics (eg, cephalosporins, quinolones, tetracyclines) & bisphosphonates (eg, alendronate, etidronate, risedronate). Additive effects w/ cholesterol medicines. Inhibits absorption of Cu & Fe.
MIMS Class
Vitamins &/or Minerals
ATC Classification
A11AA04 - multivitamins and trace elements ; Belongs to the class of multivitamins with minerals. Used as dietary supplements.
Presentation/Packing
Form
Conzace DV softcap
Packing/Price
6 × 5's (Rp112,500/boks)
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