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General precautions: Careful inquiry about any form of hypersensitivity should be made since reactions e.g. shock may occur.
Carefully administration to: Patients with a history of hypersensitivity to penicillin, patient with history of some forms of allergy e.g. bronchial asthma, rash, urticaria, patient with serious renal function disorder, and patients with poor oral nutrition, patients receiving parenteral nutrition, elderly patients or patients in a debilitated state since vitamin K.
Use in Children: Cefacef: Children with otitis media should be treated with suspension only. Safety and effectiveness of use in children <6 months have not been established.
Cefacef 200: Efficacy and safety in children aged less than 6 months have not been established (including new born and prematures).
