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Cefacef 200: Antacids: There is no significant effect on the pharmacokinetics properties in concomitant administration of cefixime with antacids.
Anticoagulants: Concomitant administration of cefixime with anticoagulants (eg, warfarin) may prolong prothrombin time, with or without bleeding.
Carbamazepine: Concomitant administration of cefixime with Carbamazepine may increase the concentration of carbamazepine in the plasma hence the concentration of carbamazepine should be monitored.
Nifedipine: Concomitant administration of cefixime with Nifedipine may increase the bioavailability of cefixime (increase concentration of peak plasma and AUC concentration).
Probenecid: Concomitant administration of cefixime with Probenecid may increase peak concentration and AUC of cefixime, also decrease renal clearance and distribution volume of the drug.
Salicylate: Concomitant administration of cefixime with Salicylate may increase concentration of cefixime in the blood.
